Associated Health Conditions Linked to HS

Hidradenitis suppurativa (HS) is more than a condition that affects the skin. Because HS is a chronic inflammatory disease, people living with HS may have a higher risk of developing other health issues over time. These conditions are often called associated health issues or comorbidities.

Not everyone with HS will develop these conditions, but understanding these risks can help you and your health care provider take better care of your whole health, not just your skin.

Why HS Can Be Linked to Other Health Conditions

HS is driven by ongoing inflammation in the body. Inflammation that lasts for a long time can affect many systems, which is why people with HS may have higher rates of certain medical conditions.

This does not mean HS causes these conditions directly, and it is not anyone’s fault. Many factors—including genetics, immune activity, and overall health—play a role.

---

Common Health Issues Associated With HS

Inflammatory and Autoimmune‑Related Conditions

People with HS may have a higher likelihood of developing other inflammatory conditions, such as:

• Inflammatory bowel disease (Crohn’s disease or ulcerative colitis)
• Arthritis or joint inflammation
• Spondyloarthritis

Other Follicle‑Related Conditions

Some people living with HS also experience other conditions that affect hair follicles. These conditions share certain underlying features, such as inflammation, but are not caused by HS, and not everyone with HS will develop them.

Pilonidal Disease (Pilonidal Cysts)
Pilonidal disease is a condition that causes painful cysts or abscesses, usually in the crease between the buttocks near the tailbone. These cysts can become inflamed, become infected, drain fluid, or come back over time.

Some people living with HS also experience pilonidal disease. Both conditions affect hair follicles and involve inflammation, which may help explain why they can occur together in some individuals. However, having HS does not mean a person will develop pilonidal disease.

Pilonidal disease is evaluated and treated differently from HS and may involve local wound care, procedures, or surgery depending on symptoms. If you notice recurrent or painful cysts in this area, it’s important to talk with a health care provider for proper evaluation and treatment.

Metabolic and Cardiovascular Health

HS has been linked with conditions that affect metabolism and heart health, including:

• Obesity
• Insulin resistance or diabetes
• High blood pressure
• High cholesterol
• Increased cardiovascular risk

Managing HS often includes paying attention to overall health, not just skin symptoms.

Hormonal and Endocrine Conditions

Some people with HS also experience hormonal or endocrine‑related conditions, such as:

• Polycystic ovary syndrome (PCOS)
• Hormonal imbalances that may affect flares

Mental and Emotional Health

Living with HS can take a significant emotional toll. People with HS may be at higher risk for:

• Depression
• Anxiety
• Social isolation
• Reduced quality of life

These experiences are common and valid, and mental health support can be an important part of HS care.

Pain, Fatigue, and Daily Functioning

Chronic pain, ongoing inflammation, and sleep disruption can contribute to:

• Fatigue
• Limited mobility
• Difficulty with work, school, or daily activities

These symptoms are part of the HS experience for many people—even when skin symptoms appear “mild.”

---

Taking Care of Your Whole Health

Because HS is associated with other health conditions, many people benefit from having both a dermatologist and a primary care provider involved in their care. Depending on your symptoms, other specialists may also be helpful.

Paying attention to your overall health can support HS management and improve quality of life.

Talking to Your Provider About Associated Health Conditions

If you have HS, it’s important to tell your health care provider about symptoms beyond your skin—such as joint pain, fatigue, mood changes, or digestive issues. These details can help guide referrals, testing, and treatment decisions.

Identifying associated health issues early can make a meaningful difference in long‑term health.

Having HS does not mean you will develop other health conditions. Many people with HS live full lives without major complications. Learning about associated health conditions is about prevention, awareness, and whole‑person care—not fear.

Living with HS?
Understanding how HS can affect your overall health is an important step. Work with your health care provider to address all aspects of your well‑being and explore trusted HS resources on the HS Foundation website.