Patient interviews highlight challenges in accessing HS care
Two genes identified as likely associates with HS
Study demonstrates decrease in work productivity due to HS
Study Shows Treatment of HS is Challenging
Initial HS lesions present with itch, but can progress to pain.
Small study shows birth control pills may be useful in the treatment of HS
Can finasteride help control hidradenitis suppurativa in women?
Biologic Therapy Not Linked to COVID-19 Severity in People With HS
An Open-Label, Prospective, Pilot Study of Hypertonic Saline for Hidradenitis Suppurativa.
Adalimumab (Humira) in combination with surgery is safe and effective to treat hidradenitis suppurativa.
This study explored whether it was safe for patients to undergo skin surgery while on adalimumab.
A number of medical conditions are associated with HS - what are they?
What happens if hidradenitis suppurativa (HS) diagnosis is delayed in children?
Women with HS were more likely to have health problems before pregnancy compared to women without HS.
Considering surgery for treating hidradenitis suppurativa (HS) can feel intimidating, especially because it can be hard to know what to expect.
This research study explored the differences in the microbiome between unaffected individuals and those with HS by obtaining bacterial swabs from the skin, inside the nose, and stool from both groups.
Research on how HS affects pregnancy is limited, which is what led researchers at Penn State College of Medicine to perform a study that compared pregnancy outcomes in patients with and without HS.
With a growing need to properly manage HS in pregnant and nursing mothers, here we discuss the article “Management of Hidradenitis Suppurativa in Pregnancy” published in 2017 that provides the most up-to-date information.
Some research studies showed the HS and IBD are more likely to happen together, but two other studies did not show a link between them. The goal of this study was to combine all of the best studies and try to clear up whether there is a link between HS and IBD.
For many patients with Hidradenitis Suppurativa (HS), pain is a problem that can lead to visits to the Emergency Department (ED).
In new, yet unpublished data from a project by Joslyn Kirby, Ashley Eichelberger, Melissa Butt, Colleen Silva, and Aretha Mosley of Penn State Hershey School of Medicine, patients shared their thoughts and experience about long-distance dermatology visits.
In a study led by Dr. Rebecca Haberman of New York University, a group of doctors studied whether people being treated for immune diseases had more severe COVID.
Infliximab is an intravenous (IV) medication that can help Hidradenitis Suppurativa (HS). The dose and timing of infliximab vary. The authors determined which dose was the best when starting treatment for HS.
In recent years, research has led to a deeper understanding of immune imbalances that may lead hidradenitis suppurativa (HS).
This study was done by researchers in the U.S.A. to find how well clinicians could measure HS using a different approach.
An early study for bermekimab shows improvement in Hidradenitis Suppurativa (HS) activity and pain scores while demonstrating safety.
This study's aim was to determine if associations between HS and various serious infections exist, using the National Inpatient Sample, a USA database of inpatient hospitalizations, between the years 2002 and 2012. The study also looked into the cost of care and length of stay of HS patients with serious infections.
HS causes pain, but few studies have looked at this aspect. The authors aimed to study pain in patients with HS.
HS lesions can come-and-go or last for months or years. HS can have times where it is worse than usual. These have been called ‘flares’. To measure flares in future studies, a definition for a flare is needed. This study was done to find out how flares were defined in past studies.
Some Hidradenitis Suppurativa patients improve when they receive infliximab, but we don’t know the proper dose of infliximab to give. This research asked whether high-dose infliximab helps Hidradenitis Suppurativa patients.
Researchers from Sweden, Ireland and the UK looked at the difference between the results of swabs and actual biopsies (tissue samples) of the skin.
This study aimed to find out how consistently 12 HS-experienced dermatologists would score 24 patients with HS, using nine different instruments.
This study, which was an international co-operation between departments in Germany, Denmark and Poland, was designed to check the agreement between different dermatologists, including those in training, on their rating of the stage of HS in 5 different patients on two separate occasions.
The researchers of this study are based in U.S.A. and aimed to find out if hidradenitis is linked with higher likelihood and costs of mental health disorders.
This study aimed to find out how the work life of people with HS was impacted compared to similar people without HS.
This study, performed by researchers from Turkey and Germany, looked at the role of a gene called MEFV gene in HS, using a group of 119 people with the disease.
This study was done to look at whether the inflammation from HS might increase the chance that someone’s immune system could go off the rails and cause lymphoma.
This study, undertaken at the ATTIKON University Hospital of Athens, Greece, suggests adalimumab could be a cost-effective and efficient treatment for HS.
The British Association of Dermatologists commissioned a HS guideline development group composed of information specialists, a HS patient and carer, and UK clinicians including dermatologists, a dermatology nurse, plastic surgeon and general practitioner (GP). The group, based in the UK, were asked to produce treatment recommendations based on a systematic review of the evidence.
Longstanding Hidradenitis Suppurativa (HS) can be associated with other complications, such as intestinal problems and skin cancer.
The unique nature of HS makes it possible to diagnose the disease using questionnaires.
In this study from a specialised HS clinic in a large UK hospital, dermatologists collaborated with psychologists to establish for the first time, the relationships between illness perceptions and health outcomes.
This is a study on the pathogenesis (causes) of hidradenitis suppurativa (HS).
The aim of this study from the German Universities of Osnabrück and Munich was to clarify whether obesity and smoking promote the Th17/Treg imbalance.
Medications targeting small proteins called cytokines could provide a possible treatment approach for HS in the future.
Population-based Clinical Practice Research Datalink study using algorithm modelling to identify the true burden of hidradenitis
Our study team based in the UK aimed to use UK electronic data recorded by General Practitioners (GPs) to identify known and previously undiagnosed cases of HS.
Prevalence of hidradenitis suppurativa among patients with Down syndrome: a population-based cross-sectional analysis
In this study, we evaluated the commonness of hidradenitis suppurativa within a large group of patients who had Down syndrome, and we used another groups of patients that did not have Down syndrome to compare findings.
Incidence of hidradenitis suppurativa among tobacco smokers: a population-based retrospective analysis in the U.S.A.
Despite a common belief that tobacco smoking increases the risk of developing the disease, the evidence linking the two is controversial.
Towards global consensus on core outcomes for hidradenitis suppurativa research: an update from the HISTORIC consensus meetings
This study aimed to find out what clinical trials for HS should measure, such as symptoms (e.g. pain, itch), physical changes (e.g. skin redness or swelling), or impact on people's lives (e.g. quality of life).
Scientists from Germany investigated whether a cytokine called interleukin-36 (IL-36) might be important in hidradenitis suppurativa (HS).
A phenotype combining hidradenitis suppurativa with Dowling–Degos disease caused by a founder mutation in PSENEN
In this present study, we showed a new genetic defect in PSENEN that can cause two diseases at once: Dowling-Degos disease and hidradenitis suppurativa.
The aim of this study from Denmark was to investigate this possible cardiovascular burden associated with HS influence on the heart's electrical activity.
Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa
This study, from Germany, sought to identify the cellular sources of IL-17 in HS, and looked at a range of other factors that might contribute to the development of the disease, including the presence and source of other proteins that are involved in HS.
In this study, 517 patients with HS and 516 patients with another skin disease, psoriasis, from 24 countries were asked about the time it took to first see a doctor and then receive a diagnosis.
According to the authors of this study, HS has been relatively neglected by society and medical research funding bodies, resulting in a lack of evidence to guide HS care. A Priority Setting Partnership (PSP) for HS was established following a model created by the James Lind Alliance which helps to bring patients, carers and clinicians together to identify and prioritise for research the treatment uncertainties which they agree are the most important.