Can Hidradenitis Suppurativa Affect Pregnancy

August 30, 2021

Research on how HS affects pregnancy is limited, which is what led researchers at Penn State College of Medicine to perform a study that compared pregnancy outcomes in patients with and without HS.
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How should Pregnant and Nursing Mothers manage Hidradenitis Suppurativa?

February 28, 2021

With a growing need to properly manage HS in pregnant and nursing mothers, here we discuss the article “Management of Hidradenitis Suppurativa in Pregnancy” published in 2017 that provides the most up-to-date information.
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How clear is the link between Hidradenitis Suppurativa and Inflammatory Bowel Disease?

February 19, 2021

Some research studies showed the HS and IBD are more likely to happen together, but two other studies did not show a link between them. The goal of this study was to combine all of the best studies and try to clear up whether there is a link between HS and IBD.
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How are Emergency Departments treating pain in Hidradenitis Suppurativa?

November 18, 2020

For many patients with Hidradenitis Suppurativa (HS), pain is a problem that can lead to visits to the Emergency Department (ED).
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Are people willing to use teledermatology for Hidradenitis Suppurativa care?

June 5, 2020

In new, yet unpublished data from a project by Joslyn Kirby, Ashley Eichelberger, Melissa Butt, Colleen Silva, and Aretha Mosley of Penn State Hershey School of Medicine, patients shared their thoughts and experience about long-distance dermatology visits.
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Is COVID more risky for people treated for an immune disease?

May 22, 2020

In a study led by Dr. Rebecca Haberman of New York University, a group of doctors studied whether people being treated for immune diseases had more severe COVID.
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What is the right dose of infliximab for Hidradenitis Suppurativa?

April 20, 2020

Infliximab is an intravenous (IV) medication that can help Hidradenitis Suppurativa (HS). The dose and timing of infliximab vary. The authors determined which dose was the best when starting treatment for HS.
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Anything new out there to help treat my HS?

April 11, 2020

In recent years, research has led to a deeper understanding of immune imbalances that may lead hidradenitis suppurativa (HS).
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A new way to measure the extent of patients’ hidradenitis suppurativa

March 31, 2020

This study was done by researchers in the U.S.A. to find how well clinicians could measure HS using a different approach.
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New drug shows promise for Hidradenitis Suppurativa treatment

February 27, 2020

An early study for bermekimab shows improvement in Hidradenitis Suppurativa (HS) activity and pain scores while demonstrating safety.
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A study into the risk of serious infections in people with hidradenitis suppurativa

February 3, 2020

This study's aim was to determine if associations between HS and various serious infections exist, using the National Inpatient Sample, a USA database of inpatient hospitalizations, between the years 2002 and 2012. The study also looked into the cost of care and length of stay of HS patients with serious infections.
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A review of use of the word ‘flare’ in hidradenitis suppurativa studies

January 2, 2020

HS lesions can come-and-go or last for months or years. HS can have times where it is worse than usual. These have been called ‘flares’. To measure flares in future studies, a definition for a flare is needed. This study was done to find out how flares were defined in past studies.
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Pain perception and depression in patients with hidradenitis suppurativa

January 2, 2020

HS causes pain, but few studies have looked at this aspect. The authors aimed to study pain in patients with HS.
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Most Hidradenitis Suppurativa patients improve with infliximab, if the dose is high enough

October 4, 2019

Some Hidradenitis Suppurativa patients improve when they receive infliximab, but we don’t know the proper dose of infliximab to give.  This research asked whether high-dose infliximab helps Hidradenitis Suppurativa patients.
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Investigation of the skin microbiome

September 1, 2019

Researchers from Sweden, Ireland and the UK looked at the difference between the results of swabs and actual biopsies (tissue samples) of the skin.
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Inter-rater reliability and agreement hidradenitis suppurativa instruments

September 1, 2019

This study aimed to find out how consistently 12 HS-experienced dermatologists would score 24 patients with HS, using nine different instruments.
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Inter- and intrarater reliability of Hurley staging

August 1, 2019

This study, which was an international co-operation between departments in Germany, Denmark and Poland, was designed to check the agreement between different dermatologists, including those in training, on their rating of the stage of HS in 5 different patients on two separate occasions.
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Association between HS and hospitalization for psychiatric disorders

August 1, 2019

The researchers of this study are based in U.S.A. and aimed to find out if hidradenitis is linked with higher likelihood and costs of mental health disorders.
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Impact of HS on work loss, indirect costs and income

July 1, 2019

This study aimed to find out how the work life of people with HS was impacted compared to similar people without HS.
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Pyrin mutations in complex hidradenitis suppurativa

June 3, 2019

This study, performed by researchers from Turkey and Germany, looked at the role of a gene called MEFV gene in HS, using a group of 119 people with the disease.
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What’s the risk of lymphoma in people with HS?

May 1, 2019

This study was done to look at whether the inflammation from HS might increase the chance that someone’s immune system could go off the rails and cause lymphoma.
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BAD guidelines for the management of HS (acne inversa) 2018

April 26, 2019

The British Association of Dermatologists commissioned a HS guideline development group composed of information specialists, a HS patient and carer, and UK clinicians including dermatologists, a dermatology nurse, plastic surgeon and general practitioner (GP). The group, based in the UK, were asked to produce treatment recommendations based on a systematic review of the evidence.
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Cost-savings in hidradenitis suppurativa

April 26, 2019

This study, undertaken at the ATTIKON University Hospital of Athens, Greece, suggests adalimumab could be a cost-effective and efficient treatment for HS.
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Does Hidradenitis Suppurativa cause skin cancer?

April 1, 2019

Longstanding Hidradenitis Suppurativa (HS) can be associated with other complications, such as intestinal problems and skin cancer.
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Patients with self-reported HS in a cohort of Danish blood donors

April 1, 2019

The unique nature of HS makes it possible to diagnose the disease using questionnaires.
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Illness perceptions and health outcomes in HS

February 4, 2019

In this study from a specialised HS clinic in a large UK hospital, dermatologists collaborated with psychologists to establish for the first time, the relationships between illness perceptions and health outcomes.
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Complement in hidradenitis suppurativa

August 24, 2018

This is a study on the pathogenesis (causes) of hidradenitis suppurativa (HS).
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Imbalanced Th17/Treg axis in hidradenitis suppurativa

August 24, 2018

The aim of this study from the German Universities of Osnabrück and Munich was to clarify whether obesity and smoking promote the Th17/Treg imbalance.
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Hidradenitis suppurativa treated with secukinumab

July 19, 2018

Medications targeting small proteins called cytokines could provide a possible treatment approach for HS in the future.
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Population-based Clinical Practice Research Datalink study using algorithm modelling to identify the true burden of hidradenitis

April 18, 2018

Our study team based in the UK aimed to use UK electronic data recorded by General Practitioners (GPs) to identify known and previously undiagnosed cases of HS.
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Incidence of hidradenitis suppurativa among tobacco smokers: a population-based retrospective analysis in the U.S.A.

March 29, 2018

Despite a common belief that tobacco smoking increases the risk of developing the disease, the evidence linking the two is controversial.
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Towards global consensus on core outcomes for hidradenitis suppurativa research: an update from the HISTORIC consensus meetings

March 29, 2018

This study aimed to find out what clinical trials for HS should measure, such as symptoms (e.g. pain, itch), physical changes (e.g. skin redness or swelling), or impact on people's lives (e.g. quality of life).
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Interleukin-36 in hidradenitis suppurativa

March 29, 2018

Scientists from Germany investigated whether a cytokine called interleukin-36 (IL-36) might be important in hidradenitis suppurativa (HS).
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Prevalence of hidradenitis suppurativa among patients with Down syndrome: a population-based cross-sectional analysis

March 29, 2018

In this study, we evaluated the commonness of hidradenitis suppurativa within a large group of patients who had Down syndrome, and we used another groups of patients that did not have Down syndrome to compare findings.
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A phenotype combining hidradenitis suppurativa with Dowling–Degos disease caused by a founder mutation in PSENEN

February 18, 2018

In this present study, we showed a new genetic defect in PSENEN that can cause two diseases at once: Dowling-Degos disease and hidradenitis suppurativa.
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Hidradenitis suppurativa and electrocardiographic changes: a cross-sectional population study

January 22, 2018

The aim of this study from Denmark was to investigate this possible cardiovascular burden associated with HS influence on the heart's electrical activity.
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Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa

October 5, 2015

This study, from Germany, sought to identify the cellular sources of IL-17 in HS, and looked at a range of other factors that might contribute to the development of the disease, including the presence and source of other proteins that are involved in HS.
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Diagnostic delay in hidradenitis suppurativa is a global problem

July 21, 2015

In this study, 517 patients with HS and 516 patients with another skin disease, psoriasis, from 24 countries were asked about the time it took to first see a doctor and then receive a diagnosis.
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The Hidradenitis Suppurativa Priority Setting Partnership

June 5, 2014

According to the authors of this study, HS has been relatively neglected by society and medical research funding bodies, resulting in a lack of evidence to guide HS care. A Priority Setting Partnership (PSP) for HS was established following a model created by the James Lind Alliance which helps to bring patients, carers and clinicians together to identify and prioritise for research the treatment uncertainties which they agree are the most important.
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